What is clobetasol propionate and what is it used for

Due to its high potency as a corticosteroid, it is available in most countries by prescription only. It should be used in as small a quantity as possible, for as short a period of time as possible. It is not recommended for use in children under 12 years old and should not be used on any open wounds, mucous membranes or the eyes. When using clobetasol propionate, the site at which it is being used, be it the skin or scalp, should not be covered or occluded. The treatment should not be used for a longer period of time than prescribed by the medical practitioner.

Metyrapone is used for the medical control of hypercortisolism in Cushing's syndrome (ACTH dependent or independent). The aim for medical treatment is to achieve pre-operative control of hypercortisolism, or for control of residual disease persisting post-operatively (TSS, adrenalectomy). It is not for long term definitive treatment/cure, only as an adjunct (surgery is the aim for cure in most causes of Cushing's syndrome). Metyrapone hence acts by inhibiting adrenal steroidogenesis. One side effect is hirsutism (in women) because of the excess androgen precursors created. The other commonly used agent for medical treatment of Cushing's is ketoconazole (an anti-fungal agent). This does not exhibit the side effect of hirsutism.

What is clobetasol propionate and what is it used for

what is clobetasol propionate and what is it used for

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