GnRH is secreted in the hypophysial portal bloodstream at the median eminence. The portal blood carries the GnRH to the pituitary gland, which contains the gonadotrope cells, where GnRH activates its own receptor, gonadotropin-releasing hormone receptor (GnRHR), a seven-transmembrane G-protein-coupled receptor that stimulates the beta isoform of Phosphoinositide phospholipase C, which goes on to mobilize calcium and protein kinase C. This results in the activation of proteins involved in the synthesis and secretion of the gonadotropins LH and FSH. GnRH is degraded by proteolysis within a few minutes.
For beginners is recommended only solo course. Dosages depend on the individual tolerability of different esters of this steroid. One can start with 300 mg once a week. After 2 weeks, the dosage can be increased to 450 mg if necessary. Additional anabolics cannot be connected, as the power of trenbolone mix cycle often enough.
More experienced athletes fit the scheme semi-combined course. In this case, to use trenbolone mix cycle 600 mg once a week, and a drug to choose one for the background. This may be a minimum testosterone enanthate 150-250 mg dose per week, or oral steroid light such as oxandrolone.
If esters are used for the drying of tren, stanozolol is suitable, preferably pelleted, but also suitable for injection. Choose the minimum dosage.
Duration of the course on the basis of such a trenbolone mix cycle – no more than 8 weeks. In contrast to the classical courses of this drug here longer use drugs because of the huge half-life Hexahydrobenzylcarbonate. The minimum duration of the course – 6 weeks.